Joint pain is one of the most common reasons people seek care — and one of the most commonly mismanaged. Standard approaches offer cortisone to suppress symptoms temporarily, or surgery to structurally alter the joint. Neither addresses the biological breakdown driving the degeneration.
Regenerative joint injections take a fundamentally different approach: deliver the biological signals needed for repair directly into the joint space, stimulate the body’s own healing mechanisms, and restore function from the inside out.
Depending on the joint, the condition, and the patient’s assessment, Chait selects from the following regenerative agents — either individually or in combination:
• Platelet Rich Plasma (PRP) — concentrated autologous growth factors for cartilage and synovial repair
• Mesenchymal Stem Cells (MSCs) — umbilical cord-derived cells for advanced degeneration and cartilage loss
• Exosomes — molecular repair signals that reduce inflammation and stimulate tissue regeneration
• Hyaluronic Acid — viscosupplementation to restore joint lubrication where indicated
Most patients experience some soreness at the injection site for 24–72 hours post-procedure — this is the inflammatory phase of the healing response and is a normal part of the regenerative process. Symptom improvement typically begins within 2–6 weeks as tissue repair progresses, with continued improvement over 3–6 months.
Unlike cortisone, which suppresses the inflammatory signal (and thus suppresses healing), regenerative joint injections work with the body’s biology — which means the improvement is structural, not temporary.
• Patients with diagnosed osteoarthritis (grade I–III) seeking to avoid or delay joint replacement
• Athletes with chronic joint degeneration limiting performance
• Post-surgical patients with incomplete recovery or persistent joint pain
• Anyone who has exhausted cortisone, physical therapy, and NSAIDs without lasting results
Regenerative joint injections are not FDA-approved as treatments for all joint conditions listed. PRP is FDA-cleared as a procedure; MSC and exosome-based injections are considered emerging therapies. This content is for educational purposes only. Evan Chait is a licensed Physical Therapist and Acupuncturist, not a medical doctor (MD). Always consult a qualified healthcare professional before pursuing any injection-based therapy. Individual results may vary.
